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Does a cup of coffee wake you up or put you to sleep? The answer to this question depends on how fast your body breaks down caffeine. Caffeine metabolism varies between people and a small change in your DNA is responsible for this difference.
Some individuals are “fast” metabolizers and clear caffeine from our systems fairly rapidly. Others are “slow” metabolizers where caffeine stays in the body for a longer period of time. This delay in clearance puts “slow” metabolizers at risk of increased blood pressure and an increased risk of heart attacks.
Take this simple DNA test to find out if you should be cutting down your caffeine intake to just one cup a day.
This DNA test detects genetic variants in the CYP1A2 gene involved in caffeine breakdown.
Individuals who inherit the “fast” metabolizer variant of the gene make sufficient amounts of enzymes to effectively clear caffeine from the body.
Individuals who inherit the “slow” metabolizer variant of CYP1A2 make reduced levels of protein, which results in prolonged presence of caffeine in their circulation. This increased stimulation of the body by caffeine is linked to several health complication.
Caffeine is a widely used psychoactive drugs around the world. However, unlike other drugs it is unregulated and readily available. While the desired effects of caffeine consumption are often combatting fatigue and drowsiness overconsumption may lead to unwanted side effects such as
- Anxiety
- Insomnia
- Increased urination
- Irritability
- GI issues
- Irregular heart rate
- Muscle twitches
Summary
Does a cup of coffee wake you up or put you to sleep? The answer to this question depends on how fast your body breaks down caffeine. Caffeine metabolism varies between people and a small change in your DNA is responsible for this difference.
Some individuals are “fast” metabolizers and clear caffeine from our systems fairly rapidly. Others are “slow” metabolizers where caffeine stays in the body for a longer period of time. This delay in clearance puts “slow” metabolizers at risk of increased blood pressure and an increased risk of heart attacks.
Take this simple DNA test to find out if you should be cutting down your caffeine intake to just one cup a day.
What's Measured?
This DNA test detects genetic variants in the CYP1A2 gene involved in caffeine breakdown.
Individuals who inherit the “fast” metabolizer variant of the gene make sufficient amounts of enzymes to effectively clear caffeine from the body.
Individuals who inherit the “slow” metabolizer variant of CYP1A2 make reduced levels of protein, which results in prolonged presence of caffeine in their circulation. This increased stimulation of the body by caffeine is linked to several health complication.
Technical Information
Caffeine is a widely used psychoactive drugs around the world. However, unlike other drugs it is unregulated and readily available. While the desired effects of caffeine consumption are often combatting fatigue and drowsiness overconsumption may lead to unwanted side effects such as
- Anxiety
- Insomnia
- Increased urination
- Irritability
- GI issues
- Irregular heart rate
- Muscle twitches
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